Answer the following questions as a final review of mutations.

1. All mutations are harmful? True or False?
   
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   False: Most mutations are neutral some are even helpful.
2. The type of gene mutations that shift the “reading frame” of the genetic message are called __________.
   
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   Frameshift
3. The gene mutation in which a segment of DNA is missing is called __________.
   
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   Deletion
4. Mutations that are in __________ cells can be passed on to offspring.
   
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   Sex cells or gametes
5. Chemical and physical agents such as pesticides, tobacco smoke, or radiation that can cause mutations are called __________.
   
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   Mutagens